Soft Tissue Compliance Detection in Minimally Invasive Surgery: Dynamic Measurement with Piezoelectric Sensor Based on Vibration Absorber Concept

Radwa Hashem, Haitham El-Hussieny, Shinjiro Umezu, Ahmed M. R. Fath El-Bab

Abstract


Recent research in the medical field has increasingly focused on tissue repair, tumor detection, and associated therapeutic techniques. A significant challenge in Minimally Invasive Surgery (MIS) is the loss of direct tactile sensation by surgeons, as they cannot physically feel the organs they operate on. Tactile feedback enhances patient safety by tissue differentiation and reducing inadvertent damage risks. Addressing this challenge, this study introduces a novel tactile sensor designed for compliance detection to enhance tactile feedback in MIS. The sensor operates on a 2-Degree-of-Freedom (2-DOF) vibration absorber system, utilizing a piezoelectric actuator with a calibrated stiffness of 188 N/m. It interprets tissue stiffness regarding a spring constant, Ko, and measures changes in soft tissue stiffness by analyzing variations in the vibration absorber frequency, specifically at the frequency which causes the first mass to exhibit zero amplitude. The effectiveness of this sensor was evaluated through tests on polydimethylsiloxane (PDMS) specimens, which were engineered to replicate varying stiffness found in human organ tissues. Young's modulus of these specimens was determined using a universal testing machine, showing a range from 10.12 to 226.89 kPa. Additionally, the sensor was applied to measure the stiffness of various chicken tissues – liver, heart, breast, and gizzard with respective Young's moduli being 1.97, 9.47, 19.55, and 96.36 kPa. This sensor successfully differentiated between tissue types non-invasively, without requiring substantial deformation or penetration of the tissues. Given its piezoelectric nature, the sensor also holds significant potential for miniaturization through Micro-Electro-Mechanical Systems technology (MEMS), broadening its applicability in surgical environments.


Keywords


Tactile Sensor; Soft Tissue; Compliance Detection; Vibration Absorber; MIS; Piezoelectric Actuator.

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References


K. Chen et al., “Robot-Assisted Minimally Invasive Breast Surgery: Recent Evidence with Comparative Clinical Outcomes,” Journal of Clinical Medicine, vol. 11, no. 7, 2022, doi: 10.3390/jcm11071827.

D. Vo, B. Jiang, T. D. Azad, N. R. Crawford, A. Bydon, and N. Theodore, “Robotic Spine Surgery: Current State in Minimally Invasive Surgery,” Global Spine J, vol. 10, no. 2, pp. 34S-40S, Apr. 2020, doi: 10.1177/2192568219878131.

E. L. Moss, G. Morgan, A. P. Martin, P. Sarhanis, and T. Ind, “Surgical trends, outcomes and disparities in minimal invasive surgery for patients with endometrial cancer in England: A retrospective cohort study,” BMJ Open, vol. 10, no. 9, Sep. 2020, doi: 10.1136/bmjopen-2019-036222.

S. Klompmaker et al., “Outcomes after minimally-invasive versus open pancreatoduodenectomy: A pan-European propensity score matched study,” Ann Surg, vol. 271, no. 2, pp. 356–363, Feb. 2020, doi: 10.1097/SLA.0000000000002850.

P. C. Van Der Sluis, D. Schizas, T. Liakakos, and R. Van Hillegersberg, “Minimally Invasive Esophagectomy,” Digestive Surgery, vol. 37, no. 2, pp. 93–100, Mar. 01, 2020. doi: 10.1159/000497456.

J. Klodmann et al., “An Introduction to Robotically Assisted Surgical Systems: Current Developments and Focus Areas of Research,” Current Robotics Reports, vol. 2, no. 3, pp. 321–332, Sep. 2021, doi: 10.1007/s43154-021-00064-3.

G. Dagnino and D. Kundrat, “Robot-assistive minimally invasive surgery: trends and future directions,” International Journal of Intelligent Robotics and Applications, 2024, doi: 10.1007/s41315-024-00341-2.

Y. Liu, R. Bao, J. Tao, J. Li, M. Dong, and C. Pan, “Recent progress in tactile sensors and their applications in intelligent systems,” Science Bulletin, vol. 65, no. 1, pp. 70–88, Jan. 15, 2020, doi: 10.1016/j.scib.2019.10.021.

J. Zhu, C. Zhou, and M. Zhang, “Recent progress in flexible tactile sensor systems: from design to application,” Soft Science, vol. 1, no. 1, 2021. doi: 10.20517/ss.2021.02.

K. Kim et al., “Tactile Avatar: Tactile Sensing System Mimicking Human Tactile Cognition,” Advanced Science, vol. 8, no. 7, Apr. 2021, doi: 10.1002/advs.202002362.

Y. Lee and J. H. Ahn, “Biomimetic Tactile Sensors Based on Nanomaterials,” ACS Nano, vol. 14, no. 2, pp. 1220–1226, Feb. 2020, doi: 10.1021/acsnano.0c00363.

S. Chun et al., “An artificial neural tactile sensing system,” Nat Electron, vol. 4, no. 6, pp. 429–438, Jun. 2021, doi: 10.1038/s41928-021-00585-x.

J. Seetohul, M. Shafiee, and K. Sirlantzis, “Augmented Reality (AR) for Surgical Robotic and Autonomous Systems: State of the Art, Challenges, and Solutions,” Sensors, vol. 23, no. 13, 2023, doi: 10.3390/s23136202.

S. H. Cho et al., “High-Resolution Tactile-Sensation Diagnostic Imaging System for Thyroid Cancer,” Sensors, vol. 23, no. 7, Apr. 2023, doi: 10.3390/s23073451.

S. Zhao, C. C. Nguyen, T. T. Hoang, T. N. Do, and H. P. Phan, “Transparent Pneumatic Tactile Sensors for Soft Biomedical Robotics,” Sensors, vol. 23, no. 12, Jun. 2023, doi: 10.3390/s23125671.

H. H. Ly, Y. Tanaka, and M. Fujiwara, “Tumor Depth and Size Perception Using a Pneumatic Tactile Display in Laparoscopic Surgery,” IEEE Access, vol. 9, pp. 167795–167811, 2021, doi: 10.1109/ACCESS.2021.3135698.

C. H. Won, J. H. Lee, and F. Saleheen, “Tactile Sensing Systems for Tumor Characterization: A Review,” IEEE Sensors Journal, vol. 21, no. 11, pp. 12578–12588, 2021, doi: 10.1109/JSEN.2021.3078369.

A. M. R. F. El Bab, K. Sugano, T. Tsuchiya, O. Tabata, M. E. H. Eltaib, and M. M. Sallam, “Micromachined tactile sensor for soft-tissue compliance detection,” Journal of Microelectromechanical Systems, vol. 21, no. 3, pp. 635–645, 2012, doi: 10.1109/JMEMS.2012.2184080.

A. M. R. Fath El Bab and K. I. E. Ahmed, “A novel tactile sensor design for stiffness detection of soft tissues,” in ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE), pp. 439–446, 2010, doi: 10.1115/IMECE2010-38794.

A. M. R. Fath El-Bab, M. E. H. Eltaib, M. M. Sallam, and O. Tabata, “Tactile Sensor for Compliance Detection,” Sensors and Materials, vol. 19, no. 3, pp. 165–177, 2007.

C. Chircov and A. M. Grumezescu, “Microelectromechanical Systems (MEMS) for Biomedical Applications,” Micromachines, vol. 13, no. 2, 2022, doi: 10.3390/mi13020164.

R. Hajare, V. Reddy, and R. Srikanth, “MEMS based sensors – A comprehensive review of commonly used fabrication techniques,” in Materials Today: Proceedings, pp. 720–730, 2021, doi: 10.1016/j.matpr.2021.05.223.

M. Shikida, Y. Hasegawa, M. S. Al Farisi, M. Matsushima, and T. Kawabe, “Advancements in MEMS technology for medical applications: Microneedles and miniaturized sensors,” Japanese Journal of Applied Physics, vol. 61, 2022.

H. Liu et al., “A Piezoresistive-based 3-axial MEMS Tactile Sensor and Its Integrated Surgical Forceps for Gastrointestinal Endoscopic Minimally Invasive Surgery,” 2024, doi: 10.21203/rs.3.rs-4483564/v1.

X. Li and H. Yang, “Enhanced Bulk Micromachining Based on MIS Process," 3D and Circuit Integration of MEMS, pp. 49-59 2021.

A. A. M. Faudzi, Y. Sabzehmeidani, and K. Suzumori, “Application of micro-electro-mechanical systems (MEMS) as sensors: A review,” Journal of Robotics and Mechatronics, vol. 32, no. 2, pp. 281–288, 2020, doi: 10.20965/jrm.2020.p0281.

U. H. Shah, R. Muthusamy, D. Gan, Y. Zweiri, and L. Seneviratne, “On the Design and Development of Vision-based Tactile Sensors,” Journal of Intelligent and Robotic Systems: Theory and Applications, vol. 102, no. 4, Aug. 2021, doi: 10.1007/s10846-021-01431-0.

P. Roberts, M. Zadan, and C. Majidi, “Soft Tactile Sensing Skins for Robotics,” Current Robotics Reports, vol. 2, no. 3, pp. 343–354, Jul. 2021, doi: 10.1007/s43154-021-00065-2.

J. Zhang, S. Lai, H. Yu, E. Wang, X. Wang, and Z. Zhu, “Fruit Classification Utilizing a Robotic Gripper with Integrated Sensors and Adaptive Grasping,” Math Probl Eng, vol. 2021, 2021, doi: 10.1155/2021/7157763.

J. Lin et al., “Non-destructive fruit firmness evaluation using a soft gripper and vision-based tactile sensing,” Comput Electron Agric, vol. 214, Nov. 2023, doi: 10.1016/j.compag.2023.108256.

C. T. Nnodim, A. M. R. Fath El-Bab, B. W. Ikua, and D. N. Sila, “Design, Simulation, and Experimental Testing of a Tactile Sensor for Fruit Ripeness Detection,” in Transactions on Engineering Technologies: World Congress on Engineering and Computer Science 2019, pp. 59–73, 2021, doi: 10.1007/978-981-15-9209-6_5.

G. Runel, N. Lopez-ramirez, J. Chlasta, and I. Masse, “Biomechanical properties of cancer cells,” Cells, vol. 10, no. 4, 2021, doi: 10.3390/cells10040887.

B. Deng, Z. Zhao, W. Kong, C. Han, X. Shen, and C. Zhou, “Biological role of matrix stiffness in tumor growth and treatment,” Journal of Translational Medicine, vol. 20, no. 1, 2022.

A. Barkovskaya, A. Buffone, M. Žídek, and V. M. Weaver, “Proteoglycans as Mediators of Cancer Tissue Mechanics,” Frontiers in Cell and Developmental Biology, vol. 8, 2020.

A. Micalet, E. Moeendarbary, and U. Cheema, “3D In Vitro Models for Investigating the Role of Stiffness in Cancer Invasion,” ACS Biomaterials Science and Engineering, vol. 9, no. 7, pp. 3729–3741, Jul. 10, 2023, doi: 10.1021/acsbiomaterials.0c01530.

M. K. Hayward, J. M. Muncie, and V. M. Weaver, “Tissue mechanics in stem cell fate, development, and cancer,” Developmental Cell, vol. 56, no. 13, pp. 1833–1847, Jul. 12, 2021.

H. T. Nia, L. L. Munn, and R. K. Jain, “Physical traits of cancer,” Science (1979), vol. 370, no. 6516, Oct. 2020, doi: 10.1126/SCIENCE.AAZ0868.

S. Ishihara and H. Haga, “Matrix Stiffness Contributes to Cancer Progression by Regulating Transcription Factors,” Cancers, vol. 14, no. 4, 2022, doi: 10.3390/cancers14041049.

F. Sauer et al., “Changes in Tissue Fluidity Predict Tumor Aggressiveness In Vivo,” Advanced Science, vol. 10, no. 26, Sep. 2023, doi: 10.1002/advs.202303523.

A. Souhami et al., “Similar performance of liver stiffness measurement and liver surface nodularity for the detection of portal hypertension in patients with hepatocellular carcinoma,” JHEP Reports, vol. 2, no. 5, Oct. 2020, doi: 10.1016/j.jhepr.2020.100147.

J. Yoo et al., “Tumor stiffness measured by shear wave elastography correlates with tumor hypoxia as well as histologic biomarkers in breast cancer,” Cancer Imaging, vol. 20, no. 1, Dec. 2020, doi: 10.1186/s40644-020-00362-7.

L. Scimeca, P. Maiolino, E. Bray, and F. Iida, “Structuring of tactile sensory information for category formation in robotics palpation,” Auton Robots, vol. 44, no. 8, pp. 1377–1393, Nov. 2020, doi: 10.1007/s10514-020-09931-y.

Y. Yang, K. L. Yung, T. W. R. Hung, and K. M. Yu, “Analyzing Liver Surface Indentation for In Vivo Refinement of Tumor Location in Minimally Invasive Surgery,” Ann Biomed Eng, vol. 49, no. 5, pp. 1402–1415, May 2021, doi: 10.1007/s10439-020-02698-4.

A. Candito et al., “Identification of tumor nodule in soft tissue: An inverse finite-element framework based on mechanical characterization,” Int J Numer Method Biomed Eng, vol. 36, no. 8, Aug. 2020, doi: 10.1002/cnm.3369.

J. Palacio-Torralba, R. L. Reuben, and Y. Chen, “A novel palpation–based method for tumor nodule quantification in soft tissue—computational framework and experimental validation,” Med Biol Eng Comput, vol. 58, no. 6, pp. 1369–1381, Jun. 2020, doi: 10.1007/s11517-020-02168-y.

A. Tsitlakidis et al., “Atomic force microscope nanoindentation analysis of diffuse astrocytic tumor elasticity: Relation with tumor histopathology,” Cancers (Basel), vol. 13, no. 18, Sep. 2021, doi: 10.3390/cancers13184539.

A. Saracino, T. J. C. Oude-Vrielink, A. Menciassi, E. Sinibaldi, and G. P. Mylonas, “Haptic Intracorporeal Palpation Using a Cable-Driven Parallel Robot: A User Study,” IEEE Trans Biomed Eng, vol. 67, no. 12, pp. 3452–3463, Dec. 2020, doi: 10.1109/TBME.2020.2987646.

M. O. Shaikh, C. M. Lin, D. H. Lee, W. F. Chiang, I. H. Chen, and C. H. Chuang, “Portable Pen-Like Device with Miniaturized Tactile Sensor for Quantitative Tissue Palpation in Oral Cancer Screening,” IEEE Sens J, vol. 20, no. 17, pp. 9610–9617, Sep. 2020, doi: 10.1109/JSEN.2020.2992767.

M. H. Lu and Y. P. Zheng, “Indentation test of soft tissues with curved substrates: A finite element study,” Medical & Biological Engineering & Computing, vol. 42, no. 4, pp.535-540, 2004.

B. Ahn and J. Kim, “Measurement and characterization of soft tissue behavior with surface deformation and force response under large deformations,” Med Image Anal, vol. 14, no. 2, pp. 138–148, Apr. 2010, doi: 10.1016/j.media.2009.10.006.

S. Kalyanam, K. S. Toohey, and M. F. Insana, “Modeling biphasic hydrogels under spherical indentation: Application to soft tissues,” Mechanics of Materials, vol. 161, Oct. 2021, doi: 10.1016/j.mechmat.2021.103987.

J. Zemła et al., “Indenting soft samples (hydrogels and cells) with cantilevers possessing various shapes of probing tip,” European Biophysics Journal, vol. 49, no. 6, pp. 485–495, Sep. 2020, doi: 10.1007/s00249-020-01456-7.

A. Fouly, M. N. A. Nasr, A. M. R. F. El Bab, and A. A. Abouelsoud, “Design, Modeling and Simulation of a Micro Tactile Sensor for Soft Tissue Stiffness Measurement with Three Tips Configuration,” in Proceedings of International Conference on Computational Intelligence, Modelling and Simulation, pp. 155–160, 2016, doi: 10.1109/CIMSim.2015.28.

D. Xu et al., “Measuring the elastic modulus of soft biomaterials using nanoindentation,” journal of the mechanical behavior of biomedical materials, vol. 133, p. 105329 Sep. 2022, doi: 10.1016/j.jmbbm.2022.105329.

C. F. Guimarães, L. Gasperini, A. P. Marques, and R. L. Reis, “The stiffness of living tissues and its implications for tissue engineering,” Nature Reviews Materials, vol. 5, no. 5, pp. 351–370, May 01, 2020. doi: 10.1038/s41578-019-0169-1.

F. J. Carter, T. G. Frank, P. J. Davies, D. Mclean, and A. Cuschieri, “Measurements and modelling of the compliance of human and porcine organs,” Medical Image Analysis, vol. 5, no, 4, pp.231-236, 2001.

A. Gefen and S. S. Margulies, “Are in vivo and in situ brain tissues mechanically similar?,” journal of biomechanics, vol. 37, no. 9, pp. 1339–1352, Sep. 2004, doi: 10.1016/j.jbiomech.2003.12.032.

Z. Taylor and K. Miller, “Reassessment of brain elasticity for analysis of biomechanisms of hydrocephalus,” journal of biomechanics, vol. 37, no. 8, pp. 1263–1269, Aug. 2004, doi: 10.1016/j.jbiomech.2003.11.027.

K. A. Athanasiou, M. P. Rosenwasser, J. A. Buckwalter, T. I. Malinin, and V. C. Mow, “Interspecies comparisons of in situ intrinsic mechanical properties of distal femoral cartilage,” Journal of orthopaedic Research, vol. 9, no. 3, pp. 330–340, 1991, doi: 10.1002/jor.1100090304.

U. Kim, Y. B. Kim, D. Y. Seok, J. So, and H. R. Choi, “A surgical palpation probe with 6-axis force/torque sensing capability for minimally invasive surgery,” IEEE Transactions on Industrial Electronics, vol. 65, no. 3, pp. 2755–2765, Mar. 2018, doi: 10.1109/TIE.2017.2739681.

J. Kim, B. K. Tay, N. Stylopoulos, D. W. Rattner, and M. A. Srinivasan, “Characterization of intra-abdominal tissues from in vivo animal experiments for surgical simulation,” In International Conference on Medical Image Computing and Computer-Assisted Intervention, pp. 206-213. 2003, doi: 10.1007/978-3-540-39899-8_26.

Y. Al-Handarish et al., “A Survey of Tactile-Sensing Systems and Their Applications in Biomedical Engineering,” Advances in Materials Science and Engineering, vol. 2020, 2020, doi: 10.1155/2020/4047937.

G. Ma and M. Soleimani, “Spectral Capacitively Coupled Electrical Resistivity Tomography for Breast Cancer Detection,” IEEE Access, vol. 8, pp. 50900–50910, 2020, doi: 10.1109/ACCESS.2020.2980112.

P. Sadeghi, K. Moran, and J. L. Robar, “Capacitive monitoring system for real-time respiratory motion monitoring during radiation therapy,” Journal of Applied Clinical Medical Physics, vol. 21, no. 9, pp. 16–24, Sep. 2020, doi: 10.1002/acm2.12958.

O. Semeniuk, P. Sadeghi, J. D. Farah, K. Moran, and J. Robar, “Performance optimization of capacitive motion sensing (CMS) system for intra-fraction motion detection during stereotactic radiosurgery,” Biomedical physics & engineering express, vol. 6, no. 1, 2020, doi: 10.1088/2057-1976/ab5bff.

G. Zonta, G. Rispoli, C. Malagù, and M. Astolfi, “Overview of Gas Sensors Focusing on Chemoresistive Ones for Cancer Detection,” Chemosensors, vol. 11, no. 10, 2023, doi: 10.3390/chemosensors11100519.

Y. Peng, N. Yang, Q. Xu, Y. Dai, and Z. Wang, “Recent advances in flexible tactile sensors for intelligent systems,” Sensors, vol. 21, no. 16, 2021, doi: 10.3390/s21165392.

M. Astolfi, G. Rispoli, G. Anania, G. Zonta, and C. Malagù, “Chemoresistive Nanosensors Employed to Detect Blood Tumor Markers in Patients Affected by Colorectal Cancer in a One-Year Follow Up,” Cancers (Basel), vol. 15, no. 6, Mar. 2023, doi: 10.3390/cancers15061797.

R. Pan, K. Hu, R. Jia, S. A. Rotenberg, D. Jiang, and M. V Mirkin, “Resistive-Pulse Sensing Inside Single Living Cells,” Journal of the American Chemical Society, vol. 142, no. 12, pp.5778-5784, 2020.

S. Pohtongkam and J. Srinonchat, “Tactile object recognition for humanoid robots using new designed piezoresistive tactile sensor and dcnn,” Sensors, vol. 21, no. 18, Sep. 2021, doi: 10.3390/s21186024.

T. D. Nguyen and J. S. Lee, “Recent development of flexible tactile sensors and their applications,” Sensors, vol. 22, no. 1, 2022, doi: 10.3390/s22010050.

W. Yue et al., “Dynamic Piezoelectric Tactile Sensor for Tissue Hardness Measurement Using Symmetrical Flexure Hinges and Anisotropic Vibration Modes,” IEEE Sensor Journal, vol. 21, no. 16, pp. 17712–17722, Aug. 2021, doi: 10.1109/JSEN.2021.3086114.

O. A. Lindahl, T. Backlund, K. Ramser, P. Liv, B. Ljungberg, and A. Bergh, “A tactile resonance sensor for prostate cancer detection - Evaluation on human prostate tissue,” Biomedical Physics & Engineering Express, vol. 7, no. 2, Mar. 2021, doi: 10.1088/2057-1976/abe681.

W. Lin, B. Wang, G. Peng, Y. Shan, H. Hu, and Z. Yang, “Skin-Inspired Piezoelectric Tactile Sensor Array with Crosstalk-Free Row+Column Electrodes for Spatiotemporally Distinguishing Diverse Stimuli,” Advanced Science, vol. 8, no. 3, Feb. 2021, doi: 10.1002/advs.202002817.

C. Ge and E. Cretu, “A Polymeric Piezoelectric Tactile Sensor Fabricated by 3D Printing and Laser Micromachining for Hardness Differentiation during Palpation,” Micromachines, vol. 13, no. 12, Dec. 2022, doi: 10.3390/mi13122164.

V. T. Rathod, “A review of acoustic impedance matching techniques for piezoelectric sensors and transducers,” Sensors, vol. 20, no. 14, pp. 1–65, 2020, doi: 10.3390/s20144051.

K. Kim, J. Kim, X. Jiang, and T. Kim, “Static Force Measurement Using Piezoelectric Sensors,” Journal of Sensors, vol. 2021, 2021, doi: 10.1155/2021/6664200.

G. Wu, M. Gotthardt, and M. Gollasch, “Assessment of nanoindentation in stiffness measurement of soft biomaterials: kidney, liver, spleen and uterus,” Scientific reports, vol. 10, no. 1, p.18784, Dec. 2020, doi: 10.1038/s41598-020-75738-7.

C. Huang, Q. Wang, M. Zhao, C. Chen, S. Pan, and M. Yuan, “Tactile Perception Technologies and Their Applications in Minimally Invasive Surgery: A Review,” Frontiers in Physiology, vol. 11, p.611596, Dec. 23, 2020, doi: 10.3389/fphys.2020.611596.

A. Gutierrez-Giles, M. A. Padilla-Castañeda, L. Alvarez-Icaza, and E. Gutierrez-Herrera, “Force-Sensorless Identification and Classification of Tissue Biomechanical Parameters for Robot-Assisted Palpation,” Sensors, vol. 22, no. 22, Nov. 2022, doi: 10.3390/s22228670.

S. S. Kumat and P. S. Shiakolas, “Design, Prototyping, and Characterization of a Micro-Force Sensor Intended for Tissue Assessment in Confined Spaces,” IEEE Sensors Journal., vol. 24, no. 12, p. 18937, 2024, doi: 10.1109/JSEN.2024.3395975.

C. Wang et al., “Tissue-Adhesive Piezoelectric Soft Sensor for In Vivo Blood Pressure Monitoring During Surgical Operation,” Advanced Functional Materials, vol. 33, no. 38, Sep. 2023.

Y. Tang, S. Liu, Y. Deng, Y. Zhang, L. Yin, and W. Zheng, “An improved method for soft tissue modeling,” Biomed Signal Process Control, vol. 65, Mar. 2021, doi: 10.1016/j.bspc.2020.102367.

Z. Nie, J. W. Kwak, M. Han, and J. A. Rogers, “Mechanically Active Materials and Devices for Bio-Interfaced Pressure Sensors – A Review,” Advanced Materials, p. 2205609, 2023, doi: 10.1002/adma.202205609.

H. Xie, J. Song, Y. Zhong, and C. Gu, “Kalman Filter Finite Element Method for Real-Time Soft Tissue Modeling,” IEEE Access, vol. 8, pp. 53471–53483, 2020, doi: 10.1109/ACCESS.2020.2981400.

L. Gan, W. Duan, T. O. Akinyemi, W. Du, O. M. Omisore, and L. Wang, “Development of a Fiber Bragg Grating-Based Force Sensor for Minimally Invasive Surgery-Case Study of Ex-Vivo Tissue Palpation,” IEEE Transactions on Instrumentation and Measurement, vol. 72, pp. 1-12, 2023, doi: 10.1109/TIM.2021.3136179.

S. Chauhan and M. Z. Ansari, “Vacuum-assisted piezoelectric cantilever mass sensor performance,” Journal of Mechanical Science and Technology, vol. 35, no. 12, pp. 5489–5494, Dec. 2021.

S. Chauhan and M. Z. Ansari, “Frequency response of a self-actuating cantilever sensor immersed in fluid,” Journal of Mechanical Science and Technology, vol. 35, no. 4, pp. 1457–1462, Apr. 2021.

X. Gao et al., “Piezoelectric Actuators and Motors: Materials, Designs, and Applications,” Advanced Materials Technologies, vol. 5, no. 1, 2020, doi: 10.1002/admt.201900716.

S. Mohith, A. R. Upadhya, K. P. Navin, S. M. Kulkarni, and M. Rao, “Recent trends in piezoelectric actuators for precision motion and their applications: a review,” Smart Materials and Structures, vol. 30, no. 1, 2021, doi: 10.1088/1361-665X/abc6b9.

K. Kapat, Q. T. H. Shubhra, M. Zhou, and S. Leeuwenburgh, “Piezoelectric Nano-Biomaterials for Biomedicine and Tissue Regeneration,” Advanced Functional Materials, vol. 30, no. 44, 2020.

P. Poillot, C. L. Le Maitre, and J. M. Huyghe, “The strain-generated electrical potential in cartilaginous tissues: a role for piezoelectricity,” Biophysical Reviews, vol. 13, no. 1, pp. 91-100, 2021.

A. Carter, K. Popowski, K. Cheng, A. Greenbaum, F. S. Ligler, and A. Moatti, “Enhancement of Bone Regeneration through the Converse Piezoelectric Effect, A Novel Approach for Applying Mechanical Stimulation,” Bioelectricity, vol. 3, no. 4, pp. 255–271, 2021.

Y. Zhang, F. Ju, X. Wei, D. Wang, and Y. Wang, “A piezoelectric tactile sensor for tissue stiffness detection with arbitrary contact angle,” Sensors, vol. 20, no. 22, pp. 1–14, Nov. 2020, doi: 10.3390/s20226607.

D. O. Uribe, J. Schoukens, and R. Stroop, “Improved Tactile Resonance Sensor for Robotic Assisted Surgery,” Mechanical Systems and Signal Processing, vol. 99, pp. 600-610, 2018, doi: 10.1016/j.ymssp.2017.07.007.

T. Sühn et al., “Vibro-acoustic sensing of tissue-instrument-interactions allows a differentiation of biological tissue in computerised palpation,” Computers in Biology and Medicine, vol. 164, p.107272, Sep. 2023, doi: 10.1016/j.compbiomed.2023.107272.

A. Esmaeel, K. I. E. Ahmed, and A. M. R. FathEl-Bab, “Determination of damping coefficient of soft tissues using piezoelectric transducer,” Biomedical Microdevices, vol. 23, no. 2, Jun. 2021, doi: 10.1007/s10544-021-00558-z.

Y. Yun et al., “A resonant tactile stiffness sensor for lump localization in robot-assisted minimally invasive surgery,” Proc Inst Mech Eng H, vol. 233, no. 9, pp. 909–920, Sep. 2019, doi: 10.1177/0954411919856519.

W. T. Thomson, Theory of Vibration with Applications. Springer US, 1993, doi: 10.1007/978-1-4899-6872-2.

H. F. M. Ali, A. M. R. Fath El-Bab, Z. Zyada, and S. M. Megahed, “Novel Contact Sensor Concept and Prototype Based on 2-DOF Vibration Absorber System,” in Proceedings - International Conference on Intelligent Systems, Modelling and Simulation, ISMS, pp. 89–94, Jul. 2016, doi: 10.1109/ISMS.2016.70.

W. C. Hayes, L. M. Keer, G. Herrmann, and L. F. Mockros, “A mathematical analysis for indentation tests of articular cartilage,” Journal of biomechanics, vol. 5, no. 5, pp. 541-551, 1972.

A. M. R. F. El et al., “Design and Simulation of a Tactile Sensor for Soft-Tissue Compliance Detection Design and Simulation of a Tactile Sensor for Soft-Tissue Compliance Detection,” IEEJ Transactions on Sensors and Micromachines, vol. 128, no. 5, pp. 186-192, 2008, doi: 10.1541/ieejsmas.128.186.

M. Zhang, Y. P. Zheng, and A. F. T. Mak, “Estimating the effective Young’s modulus of soft tissues from indentation tests-nonlinear finite element analysis of effects of friction and large deformation,” Medical engineering & physics, vol. 19, no. 6, pp. 512-517, 1997, doi: 10.1016/S1350-4533(97)00017-9.

W. F. Stokey. vibration of systems having distributed mass and elasticity. Shock and vibration handbook, pp. 7-14, 2002.

L. Zhang, F. Ju, Y. Cao, Y. Wang, and B. Chen, “A tactile sensor for measuring hardness of soft tissue with applications to minimally invasive surgery,” Sensors and Actuators A: Physical, vol. 266, pp. 197–204, Oct. 2017, doi: 10.1016/j.sna.2017.09.012.

C. H. Chuang, T. H. Li, I. C. Chou, and Y. J. Teng, “Piezoelectric tactile sensor for submucosal tumor detection in endoscopy,” Sensors and Actuators A: Physical, vol. 244, pp. 299–309, Jun. 2016, doi: 10.1016/j.sna.2016.04.020.

M. Vatankhah-Varnosfaderani et al., “Mimicking biological stress–strain behaviour with synthetic elastomers,” Nature, vol. 549, no. 7673, pp. 497–501, Sep. 2017, doi: 10.1038/nature23673.

Z. Wang. Polydimethylsiloxane mechanical properties measured by macroscopic compression and nanoindentation techniques. M.S. thesis, University of South Florida, 2011.

D. Corning, "Information about dow Corning brand silicone encapsulants," Dow Corning Electronics Division, Midland, MI, 2003.

A. P. C. Choi and Y. P. Zheng, “Estimation of Young’s modulus and Poisson’s ratio of soft tissue from indentation using two different-sized indentors: finite element analysis of the finite deformation effect,” Medical and Biological Engineering and Computing, vol. 43, pp. 258-264, 2008, doi: 10.1007/BF02345964.

A. Müller, M. C. Wapler, and U. Wallrabe, “A quick and accurate method to determine the Poisson’s ratio and the coefficient of thermal expansion of PDMS,” Soft Matter, vol. 15, no. 4, pp. 779–784, 2019, doi: 10.1039/c8sm02105h.




DOI: https://doi.org/10.18196/jrc.v5i5.22895

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Journal of Robotics and Control (JRC)

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