Respon Imun Selluler: Tinjauan Biomedik pada Pasien Tuberkulosis di RS PKU Muhammadiyah Yogyakarta
DOI:
https://doi.org/10.18196/mmjkk.v3i1.1539Keywords:
respon imun seluler, tuberkulosis paru jumlah leukosit, hitung jenis leukosit (HJL), kecepatan endap darah (KED), lung tuberculosis, cellular immune response, leucocyte count, defferential leukocyte count, erythrocyte sedimentation rate (ESR)Abstract
Tuberculosis (TB) is a disease which is still commonly found in developing countries including Indonesia, both in children and adults. The objective of this study was to reveal cellular immune response which include leukocyte count, defferential leukocyte count and erythrocyte sedimentation rate (ESR) in TB patients in PKU Muhammadiyah Hospital of Yogyakarta. Secondary data was taken from the medical records of lung TB patients whose age ranged from 6 months old until 82 years old. The patients were diagnosed as lung TB based on clinical, immunologic, radiologic and bacte- riologic examinations. ESR was examined using Westergen method and leu-cocyte count with Turk method, while defferential leucocyte count using manual method. The result of this study in leukocyte count showed leucopenia (4,28%), normo (71,4%), leukocytosis (24,2%o). The defferential leukocyte count showed neutrophilia (55,6%), limphocytosis (22,7%), normo (20,2%) and eosinophilia (1,26%). The ESR examination showed an increase in 80% cases. All the re¬sults described the first condition of TB patients who came to PKU Muhammadiyah Hospital studied from their medical records.
Tuberkulosis (TB) masih merupakan penyakit yang banyak didapatkan di negara sedang berkembang termasuk di Indonesia, baik pada anak-anak maupun orang dewasa. Tujuan penelitian ini adalah untuk mengungkapkan respon imun seluler yang meliputi jumlah leukosit dan hitung jenis leukosit (HJL), dan kecepatan endap dsrah (KED pada penderita TB di RS PKU Muhammadiyah Yogyakarta. Subyek penelitian adalah pasien TB paru berusia 6 bulan sampai dengan 82 nhun dengan mengambil sampel data sekunder dari catatan medik penderita yang islah didiagnosis sebagai TB paru, baik secara klinis, imunologis, radiologis maupun bakteriologis. Penghitungan jumlah leukosit dengan metode Turk dan HJL dengan sara manual. KED dihitung dengan metode Westergen. Hasil penelitian menunjukkan leukopenia (4,28), normo (71,4%) dan leukositosis (24,2%), HJL menunjukkan neutrofilia (55,6%), limfositosis (22,7%), normo (20,2%) ian eosinofilia (1,26%). Hasil Penelitian menunjukkan peningkatan KED (80%). Hasil penelitian ini menguraikan kondisi awal pasien TB yang datang ke RS PKU Muhammadiyah Yogyakarta yang dikaji dari buku rekam medis.
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