Pengaruh Konsentrasi Lidokain Terhadap Bakteri Streptococcus Mutans

Authors

  • Muhammad Wildan Hari Subagya Haryon Mahasiswa Program Studi Kedokteran Gigi Universitas Muhammadiyah Yogyakarta
  • Poerwati Soetji Rahayoe Dosen Fakultas Kedokteran Gigi Universitas Gadjah Mada

DOI:

https://doi.org/10.18196/mmjkk.v7i2%20(s).9430

Keywords:

Antibacterial, Lidocaine, Streptococcus mutans

Abstract

Lidocaine is one of local anaesthesia agent that has antibacterial power: Streptococcus mutans are normal bacterium in oral cavity. The purpose of this research are for knowing the effect of lidocaine concentration in inhibiting and killing power to Streptococcus mutans. The research design use eksperimental design, with dilution liquid and solid method which used to know inhibiting power and or killing power concentration sample. Bacterial test that used in this research has been compared with McFarland standard liquid with has concentration of] 0‘ CF U/ML. The samples concentration are 2%, I %, 0,5 %, 0,25%, 0, 125%, 0,0625%, 0,03125%, 0, 01 5625%, 0, 00781 2%. Statistic test by Kruskal-Wallis and Mann- Whitney.

The research result said that there is a relation between lidocaine concentration with Streptococcus mutans bacterial with inhibiting power on 2 %, I % and 0,5 % and with minimal inhibiting activity at 0,5% (p<0,05). There is no result about killing power in lidocaine concentration to Streptococcus mutans bacterial ( p>0, 05).

Author Biography

Muhammad Wildan Hari Subagya Haryon, Mahasiswa Program Studi Kedokteran Gigi Universitas Muhammadiyah Yogyakarta

References

Anonymous, 2007b, Using Antibiotics and Chemical Agents to Control Bacteria, Kaisers microbiology, http://student.ccbcmd.edu/courses/bio 141/lecguide/gnit2/control/antibio.html >[diakses 21 November 2007]

Brock, 2007, Cell Biology, http://people.uleth.ca~selibl/Biol3200/CourseNotes/CellBiolCh4.pdf > [diakses 26 November 2007]

Gajraj, R.J., Kenny, G.N.C, Gillespie, J.A., Hodson, M.J. and Scott, N.B., 1998, Antibacterial Activity of Lidocaine in Mixtures with Diprivan, British Journal of Anaesthesia, 81 : 444-448.

Goldin, AA., 2007, Bacterial Anatomy, Bacterial Anatomy Lecture, http://jeeves.mmg.uci.edu/medmicro/Lectures/assets/1Bacterial%20Angtomy%20legture. [diakses 26 November 2007]

Howe, G.L., Whitehead, F.l.H., 1990, Local anaesthesia in Dentistry (terj.) ed.3, Hipokrates, Jakarta, h. 25-26.

Kaya, K., Dogan, B., Gunaydin, B., Bozdayi, G., Kokten, G. and Rota, S., 2007, Comparison of the Antibacterial Effects of Two Local Anesthetics : Lidocaine and Articaine, Turk J Med Sci, 37(1): 7-10.

Pedersen, G.W., 1988, Oral Surgery (terj.), Penerbit Buku Kedokteran EGC, Jakarta, h. 1-13.

Downloads

Published

2007-07-23

Issue

Section

Research