The Formulation of Lotion Preparations of Betel Leaf Extract (Piper betle)

Ingenida Hadning, Putri Kurnyaningtyas, Muhammad Thesa Ghozali

Abstract


Betel leaf (Piper betle) contains an essential oil that has extreme antiseptic power (bactericidal and fungicidal). Betel leaf (Piper betle) can be used in the treatment of Tinea versicolor or known in the community as panu. However, its use in the form of leaves is considered impractical by the public and also difficult to obtain. This research formulated betel leaf (Piper betle) into lotion preparations, so its use in the community can be more practical. This study aims to determine the type and concentration of the suspending agent used to produce lotion preparations from betel leaf extract (Piper betle), which has optimal physical quality. This research was an experimental study. The distillation of betel leaf (Piper betle) was carried out to get essential oils. The essential oils of betel leaf (Piper betle), which was used as an active substance in formulations, was 5%. Suspending agents that were used in this study were Arabic gum with concentrations of 10%, 15%, 20%, and CMC Na, with concentrations of 0.25%, 0.5%, and 1%. The formulation of lotion preparations included organoleptic observation, pH test, homogeneity test, and adhesion test. Based on the physical quality test of the lotion preparations that had been conducted, it can be concluded that the lotion preparations of betel leaf extract with 20% concentration of Arabic Gum suspending agent had physical qualities in accordance with lotion dosage criteria.


Keywords


betel leaf extract; formulation; lotion; Piper betle

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References


Dorland, W. N. (2012). Kamus saku kedokteran Dorland edisi 28. Jakarta: EGC.

Sahoo, A. K., & Mahajan, R. (2016). Management of tinea corporis, tinea cruris, and tinea pedis: A comprehensive review. Indian dermatology online journal, 7(2), p. 77.

Wantini, S., Violita, Y., & Sulistianingsih, E. (2017). Perbandingan Uji Efektivitas Air Perasan Lengkuas Merah (Alpinia purpurata K. Schum) Dengan Air Perasan Lengkuas Putih (Alpinia galnga L. Wild) Terhadap Pertumbuhan Jamur Malassezia furfur Penyebab Panu. Jurnal Analis Kesehatan, 2(2), pp. 282-289.

Ardelia, P. I., Andrini, F., & Hamidy, M. Y. (2017). Aktivitas Antijamur Air Perasan Daun Seledri (Apium graveolens L.) Terhadap Candida albicans Secara In Vitro. Jurnal Ilmu Kedokteran, 4(2), pp. 102-107.

Hariyanto, S., 2012. Ensiklopedia Tanaman Obat Indonesia. Jakarta: Mitra Setia.

Yuniarti, T, 2008. Ensiklopedia Tanaman Obat Tradisional. Yogyakarta: Media Presindo.

Erwiyani, A. R., Luhurningtyas, F. P., & Sunnah, I. (2017). Optimasi formula sediaan krim ekstrak etanol daun alpukat (Persea americana Mill) dan daun sirih hijau (Piper betle Linn). Cendekia Journal of Pharmacy, 1(1), pp. 77-86.

Nurhidayati, L. Y. D., & Mariani, S. (2012). Penetapan Kadar Eugenol dalam Minyak Atsiri dari Daun Sirih Merah ( Piper cf fragile Benth.) dan Sirih Hijau ( Piper betle L.) secara Kromatografi Gas. In Seminar Nasional POKJANAS TOI XLII.

Octavia, M. D., Halim, A., & Afrinda, M. (2017). Karakterisasi Kompleks Inklusi Simvastatin–Β-Siklodekstrin Metoda Co-Grinding dengan Variasi Waktu Penggilingan. Jurnal Farmasi Higea, 7(1), pp. 30-43.

Anggraini, D., & Kasmawati, L. Y. (2017). Formulasi Gel Sarang Burung Walet Putih (Aerodramus fushipagus) dan Uji Penyembuhan Luka Bakar Derajat II pada Mencit. Jurnal Sains Farmasi & Klinis, 4(1), pp. 55-60.

Fajriyah, U., Astuti, I. Y., & Hartanti, D. (2010). Formulasi Losion Ekstrak Herba Tali Putri (Cuscuta Australis R. Br.) Dan Aktivitas Antioksidan Secara in Vitro. PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), 7(01), pp. 24-34.

Fitriana, A. Y., Wahyuningrum, R., & Sudarso, S. (2012). Daya Repelan Dan Uji Iritasi Formula Lotion Ekstrak Etanol Daun Sirih (Piper Betle Linn) Dengan Variasi Basis Lanolin Terhadap Nyamuk Aedes Aegypti. PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), 9(02), pp. 39-57.

Siregar, C. J., & Wikarsa, S. (2010). Teknologi Farmasi Sediaan Tablet Dasar-Dasar Praktis. Jakarta: EGC.

Rowe, R. C., Sheskey, P., & Quinn, M. (2009). Handbook of pharmaceutical excipients. London: Libros Digitales-Pharmaceutical Press.

Hadning, I., (2016). Formulasi dan uji stabilita fisik sediaan oral emulsi virgin coconut oil. Mutiara Medika: Jurnal Kedokteran dan Kesehatan, 11(2), pp. 88-100.

Nurlina, N., Tomagola, M. I., Hasyim, N., & Rahman, F. (2014). Formulasi suspensi kering kombinasi ekstrak etanol kunyit (Curcuma longa L.) dan serbuk daging buah pisang kepok (Musa balbisiana Colla.) dengan variasi bahan pensuspensi. As-Syifaa Jurnal Farmasi, 6(2), pp. 166-177.

Yuliana, A., Nurdianti, L., Fitriani, F., & Amin, S. (2020). Formulasi Dan Evaluasi Kosmetik Dekoratif Perona Pipi Dari Ekstrak Angkak (Monascus Purpureus) Sebagai Pewarna Dengan Menggunakan Lesitin Sebagai Pelembab Kulit. FITOFARMAKA: Jurnal Ilmiah Farmasi, 10(1), pp. 1-11.




DOI: https://doi.org/10.18196/jfaps.010104

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