Korelasi Gambaran Ultrasonografi Hepar dengan Kadar Alkali Fosfatase Pasien Klinis Hepatitis
DOI:
https://doi.org/10.18196/mmjkk.v13i1.1049Keywords:
ultrasonografi hepar, alkali fosfatase, hepatitis, liver ultrasound, alkaline phosphataseAbstract
Hepatitis adalah penyakit peradangan atau infeksi hati, dengan penyebab virus, bakteri, jamur, parasit dari obat-obatan. Pemeriksaan penunjang diagnostik hepatitis adalah tes fungsi hati, salah satunya adalah alkali fosfatase, yaitu enzim yang berhubungan dengan penanda adanya penyumbatan pada kantung empedu (kolestasis) dan sensitif untuk mendeteksi beragam jenis penyakit parenkim hati. Pemeriksaan ultrasonografi (USG) dilakukan untuk mendeteksi adanya kelainan organ seperti gambaran ekhostruktur, ukuran, permukaan hepar dan vesika felea. Tujuan penelitian ini adalah untuk mengetahui korelasi antara gambaran USG hepar dengan kadar alkali fosfatase pada pasien klinis hepatitis. Jenis penelitian ini observasional analitik dengan desain cross sectional, menggunakan data rekam medis. Data penelitian berjumlah 35. Analisis data menggunakan uji Spearman dan uji Lambda. Hasil penelitian menunjukkan terdapat korelasi antara kadar alkali fosfatase dengan gambaran USG hepar yang meliputi: ekhostruktur (r=0,094, p=0,590), ukuran (r=0,333, p=0,050) dan permukaan hepar (r=0,324, p=0 ,057), vesika felea (r=0,615, p=0 ,001). Disimpulkan bahwa tidak terdapat korelasi yang bermakna antara gambaran ekhostruktur, permukaan, dan ukuran hepar dengan kadar alkali fosfatase, tapi terdapat korelasi yang bermakna antara gambaran vesika felea dengan kadar alkali fosfatase pada pasien klinis hepatitis.
Hepatitis is the inflammation or infection of the liver. The causes viruses, bacteria, fungi, parasites and drugs. Additional examination a diagnostic of hepatitis are liver function test, such as Alkaline Phosphatase, Alkaline Phosphatase is an enzyme associated with markers of the blockage of the gallbladder (cholestasis) and sensitive for the detection of various types of liver parenchymal disease. Ultrasonography (USG) is to see a imaging ekhostruktur, size, surface liver and vesica felea. The aim of research to know the correlation between liver ultrasound imaging with Alkaline Phosphatase level in clinical hepatitis patient. This study was observational analytic cross-sectional design, using medical records. Research data 35. The analyzes were conducted using Spearmen test and Lambda test. The results showed a correlation between levels Alkaline Phosphatase with an ultrasound image of the liver include: echostructure (r= 0.094, p= 0.590), size (r= 0.333, p= 0.050) and the surface of the liver (r= 0.324, p= 0.057), vesica felea (r= 0.615, p= 0.001). It can concluded that there was no significant correlation between the image echostruktur, surface, and the size of the liver with levels of Alkaline Phosphatase, but there is a significant correlation between the vesica fellea features with Alkaline Phosphatase levels in patients with clinical hepatitis.
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