Perbandingan Pemberian Ekstrak Kayu Siwak (Salvadora persica) 50% Dan Larutan Sodium Fluorida 2% Terhadap Ketahanan Dentin Gigi Rattus norvegicus
Abstract
Siwak memiliki banyak kegtmaan bagi kesehatan gigi dan mulut, diantaranya menghilangkan stain, memutihkan gigi, mengurangi plak dan gingivitis juga sebagai antitumor, efek bakteriosidal dan menstimulasi pertahanan gingiva, membantu kerusakan jaringan, serta menghambat pembentukan karang gigi. Sedangkan sodium fluorida terdapat khusus pada tulang dan khususnya di email dan dentin gigi dan digunakan untuk mencegah karies gigi, menghambat dekalsifikasi, menstimulasi remineralis asi serta menghambat pembentukan asam oleh kuman mulut.
Penelitian ini bertujuan untuk menganalisis perbandingan antara penggunaan ekstrak kayu siwak 50% dan larutan sodium fluorida 2% terhadap ketahanan asam dentin gigi Rattus norvegicus. Penelitian dilakukan secara eksperimental laboratoris secara in vitro dan menggunakan 10 Rattus norvegicus. Perlakuan yang diberikan adalah pembeiian ekstrak kayu siwak secara topikal pada gigi rahang bawah 5 Rattus norvegicus dan pemberian larutan sodium fluorida secara topikal pada gigi rahang bawah 5 Rattus norvegicus. Pemberian ekstrak kayu siwak 5 0% dan larutan sodium fluoiida 2% dilakukan sejak Rattus norvegicus berumur 20 hari sampai Rattus norvegicus berumur 50 hari. Kemudian gigi Rattus norvegicus dietsa dengan gel asam fosfat 37% selama 60 detik lalu dirontgen digital periapikal dan di skor untuk mendapatkan data masing-masing vatiabel selanjutnya dilakukan uji statistik Mann- Whitney Test.
Hasil uji statistik dengan Mann- Whitney Test didapat (p=0,221) karena (p>0,05) maka eksnak kayu siwak 50% mempunyai pengaruh yang tidak signifikan terhadap ketahanan dentin gigi Rattus norvegicus dibandingkan dengan larutan sodium fluorida 2%.
Hasil penelitian menunjukkan bahwa ekstrak kayu siwak 50% dan larutan sodium Fluorida 2% memiliki pengaruh yang tidak berbeda secara signifikan terhadap ketahahan dentin gigi Rattus norvegicus.
Keywords
Full Text:
PDFReferences
Al-Khateeb, T.L., O’Mullane, D.M., Whelton, H., Sulaiman, M.l. (1991). Research Journal: Periodontal Treatment Needs Among Saudi Arabian Adults and Their Relationship to The Use of Miswak. Jeddah, Kingdom of Saudi Arabia. King Abdul Aziz University.
Al-Lafi, T., & Ababneh, H. (1995). Research Journal: The Effect of The Extract of The Miswak (Chewing Stick) Used in Jordan and The Middle East on Oral Bacteria. Carddiff, United Kingdom. University of Wales College of Medicine, Dental School, Department of Periodontology. http//:www.sdsjournal.org
Almas, K. (1995). The Effect of Salvadora Persica Extract (MiswakK) and Chlorexidine Gluconate on Human Dentin. Riyadh, Kingdom of Saudi Arabia. Department of Preventive Dental Sciences, King Saud University College of Dentistry. Riyadh. http://faculty.ksu.edu.sa
Almas, K. (2002). The Journal of Contemporary Dental Practice: The Effect of Salvadora Persica Extract (MiswakK) and Chlorexidine Gluconate on Human Dentin: A SEM study, www.thejcdp.com Vol. 3. No. 3.
Akpata, E.S., &Akinrimisi, E.O. (1977). Antibacterial properties of extract from some African chewing sticks. Oral Surg. Hlm. 717-722.
Anonim. (2002). Kamus Kedokteran Dorland. Ed. Ke-29.
Arens, J., & Ten Cate, J.M. (1982). Pengaruh Fluor Pada Remineralisasi Enamel. Dalam Prevensi Dalam Kedokteran Gigi dan Dasar Ilmiahnya. K.G. Konig dan H. Hoogendoorn. (Editor). Jakarta. PT.Denta. Hlm.24.
Al Sadhan, Raed, BDS, &Almas, Khalid, BDS, MSC, DDPH RCS, FRACDS, FDS RCSED, FICD. (1998). Miswak (chewing Stick): A Cultural And Scientific Heritage. King Saud University College of Dentistry. Riyadh. http://faculty.ksu.edu.sa
Al-Bagieh, N.H & Weinberg, E.D. (1988). Benzylisothiocya-nate: a possible agent for controlling dental caries. Microbios. http://faculty.ksu.edu.sa
Baum, Philips, Lund. (1997). Textbook of Operative Dentistry (Tarigan, R, penerjemah). EGC. Jakarta.
Besford, J. (1996). Mengenal GigiAnda Petunjuk Bagi Orang Tua. (terj). Arcan. Jakarta.
Carlo, C.T., Ciancio, S.G., & Seyrek, S.K. (1982). An evaluation of iontophoretic application of fluoride for tooth desensitization. JADA.
Chow, L.C. (1990). Tooth-bound fluoride and dental caries. J Dent Res 69 (Spec Issue): 595-600. http://www.fdiworldental.org
Craig, Powers, Wataha., (2000). Dental Materials Properties and Manipulation, Edisl ke-7., America Mosby, Inc., St. Louis, Missouri. Hlm 73.
Dewes, C. (1989). Fluorides : Mechanisms of action and recommendations for use J Dent Res, 55:721-723. http://medicaljournal-ias.org
El-Mostehy, DR. M., Ragaii, A.A., Al- Jassem, l.A., Al-Yassin, A.R., El-Gindy, E., Shoukry. (1998). MiswakAs an Oral Health Device (Preliminary Chemical And Clinical Evaluation). Quwait. Department of Odontology, Faculty of Dentistry, University of Kuwait. http://faculty.ksu.edu.sa
El Mostehy, M.R., Al-Jassem, A.A., Al- Yassin, l.A, (1983). Miswak as an oral health device. Preliminary chemical and clinical evaluation. Hamdard. Hlm.41-50. http://faculty.ksu.edu.sa
Farooqi, M.l.H & Srivastava, J.G. (1968). The toothbrush tree (Salvadora persica) Quart. J. Crude Res. http://faculty.ksu.edu.sa
Fatmasari, D., Sunarjo, L., & Aryanti, E. (2003) Pengaruh Metode Menggosok Gigi terhadap Penyerapan Fluoride. Majalah llmu Kedokteran Gigi 5 (9) : 231- 4.
Finkleman, R.D., Mohan, S., Jennings, J.C., Taylor, A.K., Jepsen, S., & Baylink, D.J. (1990). Quantitation of growth factors IGF-l, SGF/IGF-ll and TGF-I3 in human dentin. J Bone Miner Res 5: 717-723. http://herkules.oulu.fi
Finn, Sidney B. (2003) Clinical Pedodontics. Ed. Ke-4. Philadelphia. W.B.Saunders Company. Hlm.508-509.
Ford, T.R. (1993). Restorasi Gigi. Ed. Ke-1. (Terj). EGC. Jakarta.
Gazi, M.l., Davies, T.J., & Al-Bagieh N dan Cox SW. (1992). The immediate and medium- term effects of Miswak on the composition of mixed saliva. J Clin Perio- dontol. http://faculty.ksu.edu.sa
Hamilton, l.R., Mckee, A.S., & Marsh, P.D. (1990). Prevention of population shifts in oral mikrobial communities in vitro by low fluoride concentrations. J Dent Res.
Hardie, J., & Ahmed, K., (1995). The Miswak As an Aid in Oral Hygiene. Kingdom of Saudi Arabia. J Philipp Dental Association.
Hietala, E-L. & Larmas, M. (1992). The effect of ovariectomy on dentin formation and caries in adult rats. Acta Odontol Scand 50: 337-343. http://herkules.oulu.fi
Homer, K.A., Manji, F., & Bighto, D. (1992). Inhibitory properties and glycosides activities of Prophyromonus gingivallis, Bacteroides and Treponema dentealis. J Clin Periodontol.; 19: 305-310.
ltjingningsih, drg. W.H. (1995). Anatomi Gigi. EGC. Jakarta.
Katzung, B.G. (1998). Farmakologi klinik IV. Dekker. Appleton and Lange.
Kidd, E.A.M., & Bechal, S.J. (1992). Dasar-dasar Karies Penyakit dan Penanggulangannya. Penerjemah. Sumawinata, N., dan Faruk, S. EGC. Jakarta. Hlm. 100-134
Killian, M., Thylstrup, A., & Fejerskov O. (1979). Predominant plaque flora of Tanzanian children exposed to high and low water fluoride oonoentrations. Caries Res.
Kohn, D.F., & Barthold , S.W. (1984).Biology and Disease of Rats. Fox, J.G, Cohei, B.J., Loew, F.M. (Eds.). Laboratory Animal Medicine, Academic Press. lnc., Fluorida. Hlm. 91-120.
Koulourides, T. (1990). Summary of session ll: fluoride and the caries process. J Dent Res 69 (Spec Issue): 558. http://www.fdiworldentaI.org
Kortelainen, S. & Larmas, M. (1994). Effect of fluoride on the rate of dentin apposition and caries progression in young and old Wistar rats. Scand J Dent Res 102: 30-33. http://herkules.oulu.fi
Lestari, L., & Boesro, S. (1999).Pencegahan Karies Gigi dengan Kumur Larutan Fluordan Pasta Gigi Berfluor di SDN. Grogol 01, 03 dan 09 Jakarta Barat. Dalam Majalah llmiah Kedokteran Gigi Fakultas Kedokteran Gigi USAKTI. Mellberg, dkk, 1983; Carlos, cit. Wei, 1985; WHO, 1994. (Eds). Vol. 1. Ed. Khusus FORIL VI. ISSN. 0215-126X. Hlm. 78.
McCabe, J.F. (1990). Applied Dental Materials. Ed. Ke-7. London. Blackwell Scientific Publications. Hlm. 157-160.
Newbrun, E., D.M.D., Ph.D. (2002). Topical fluorides in caries prevention and management: A North American perspective. Department of Stomatology School of Dentistry. University of California San Francisco. San Francisco. http://www.nidcr.nih.gov
Schour, I., & Massler, M. (1971). The Teeth. The Rat in Laboratori Investigation. Farris, E.J., dan Graffith, J.Q. (Editors). Ed. Ke-2. Newyork. Hafner Publishing Company. Hlm. 104-135.
Selvig, K.A., Sand, H.F., Morch, T. (1968). The Effect of Topically Applied Fluorides on The Acid Resistance of Human Dentin Studied by Means of Microradiography. Seltzer, S.-Dan Bender, l:B. (Editors). J.B. Lippincott Company. Philadelpia.
Smith, J.B., & Mangkoewidjojo, S. (1988). Pemeliharaan Pembiakan dan Penggunaan Hewan Percobaan di Daerah. Jakarta. Penerbit Ul. Hlm. 37-38, 44.
Tal, M., Oron, M., Gedalia|., Erlich, J. (1976). X-ray Diffraction and Scanning Electron Microscope Investigation of Fluon'de- Treated Dentin in Man. Seltzer, S. Dan Bender, l:B. (Editors). J.B. Lippincott Company. Philadelpia.
Tarigan, R. (1990) Karies Gigi. Cetakan (1). Jakarta. Hipokrates.Tjitrosoepomo, G. (1998). Taksonomi Tumbuhan 2. Yogyakarta. Gadjah Mada University. Press.
Wolinsky LE, Sote E0. (1984). Caries Res: Isolation of natural plaque inhibiting substances from Nigerian chewing sticks. Hlm. 216-225. http://www.thejcdp.com
Ekstrand, K.R., Ricketts, D.N., Kidd, E.A. (1997). Reproducibility and accuracy of three methods for assessment of demineraliza-tion depth on the occlusal surface: an in vitro examination. Wolwacz, Victor Ferras., Chapper, Ana., Bussato, Adair. L.S., Barbosa, Avebiades. N., (2004). Correlation between visual and radiographic examinations of non- cavitated occlusal caries lesions – an in vivo study. Braz Oral Res;1 8(2): 145-9
Wu CD, Darout IA, Skaug N. (2001). Chewing sticks: timeless natural toothbrushes for oral cleansing. J Periodont Res. Hlm. 275-284. http://vww.thejcdp.com
DOI: https://doi.org/10.18196/mmjkk.v7i2%20(s).9429
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Editorial Office:
Journal Room, G1 (Biomedic) Building, Ground Floor, Faculty of Medicine and Health Science Universitas Muhammadiyah Yogyakarta,
Jalan Lingkar Selatan (Brawijaya), Tamantirto, Kasihan, Bantul, Daerah Istimewa Yogyakarta, Indonesia
Phone: +62 274 387 656 (ext: 231)
WA : +62 811-2650-303
Website: http://journal.umy.ac.id/index.php/mm
E-mail: mmjkk@umy.university
Mutiara Medika: Jurnal Kedokteran dan Kesehatan is licensed under a Creative Commons Attribution 4.0 International License. View My Stats