EffectOf Panax Ginseng Extract For The Increased Number Of Fibroblasts Cells After Tooth Extraction

Abstract

The process of tooth extraction can lead to injury. One of the factors that influence
the process of wound healing after tooth extraction is the number of fibroblast
cells. The content of saponins can increase the number of fibroblasts cells after
tooth extraction. Asian ginseng plants known to contain saponins (ginsenoside).
The purpose of this study was to determine the effect of Asian ginseng extract
(Panax ginseng extract) for the increased number of fibroblasts cells after tooth
extraction. The research method used is in vivo experimental design with the
design methods Randomized Post Test Only Control Group Design. In this study
used twentty male rattus novergicus and divided into four group, consisting of
control group (K1) were not given Asian ginseng extract, treatment groups
number one (K2) were given 25mg/Rattus novergicus/day doses of Asian
ginseng, treatment groups number two (K3) were given 50mg/ Rattus
novergicus/day doses of Asian ginseng, and treatment groups number three (K4)
were given 75mg/Rattus novergicus/day doses of Asian ginseng. Histopathologic
preparations used for counting the number of fibroblasts cells. The results of
statistical tests indicate there are differences in the number of fibroblast cells in
Rattus novergicus between the four different groups (ANOVA, p <0.05) and there
is a very strong correlation between increasing doses of ginseng extract with a
number of fibroblast cells in Rattus novergicus tooth socket (Pearson, R = 0.915 p
<0.05). The conclusion of this study is Asian ginseng extract can increase the
number of fibroblasts in the tooth socket after tooth extraction, it is recommended
that research about the amount of saponin in Asian Ginseng extract